Dengue Virus

 (DENV) is the cause of dengue fever. It is a mosquito-borne single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. It binds to Langerhans cells, which it uses as host cells for viral replication.

Trivia

 * A virion of dengue is depicted as a mask of a Tengu, a spirit or yōkai from Japanese folklore. This is a visual pun on the phonetic similarity between the words "Tengu" and "dengue" (デング) in Japanese.
 * Cells infected by the virus are even granted the gust-blowing abilities of a Tengu's aralia leaf.
 * The way the mask latches onto its target's face may be a reference to the Stone Mask from JoJo's Bizarre Adventure.